Sale defied Jacques Vermeulen's first-half red card to dispatch Saracens 21-17 with Tom O'Flaherty emerging as the star of a slugfest at StoneX Stadium.
Bath secured home advantage in the Gallagher Prem play-offs after beating Leicester 24-22 at a rainswept Recreation Ground.
Alex Hearle scored a hat-trick as Newcastle staged an incredible second-half comeback to secure a 45-42 triumph over Sale at Kingston Park.
Leicester secured a place in the Prem Rugby play-offs with an emphatic 47-33 bonus-point victory at Sale that left them a point behind second-placed Bath.
Fin Smith's last-second penalty snatched a breathless 41-38 victory for Prem Rugby leaders Northampton Saints against second-placed Bath at Franklin's Gardens.
Noah Caluori claimed another remarkable five-try haul against Sale as Saracens kept alive their outside hopes of reaching the Prem play-offs with a stunning 85-19 win.
Sale hooker Nathan Jibulu has received a six-week ban for biting Harlequins prop Will Hobson.
This was supposed to be where Courtney Lawes ended his 20-year playing career.
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